PARLIAMENTARY DEBATE
Sepsis Awareness Month - 15 September 2026 (Commons/Commons Chamber)

Debate Detail

Contributions from Dr Caroline Johnson, are highlighted with a yellow border.
Con
Mike Wood
Kingswinford and South Staffordshire
I beg to move,

That this House has considered World Sepsis Awareness Month.

As co-chair of the all-party parliamentary group on sepsis, I would like to begin by expressing my gratitude to the Backbench Business Committee for granting time for this debate. To the best of my knowledge, this is the very first debate in the House of Commons Chamber dedicated to sepsis. In the past, this devastating condition has been discussed only in Westminster Hall debates or raised through brief interventions and questions. Having sepsis debated on the Floor of the main Chamber during Sepsis Awareness Month is a major milestone, not only for Parliament but for the clinicians, charities and bereaved families across the country who have campaigned tirelessly to bring this condition out of the shadows.

I would also like to thank the co-sponsors of this debate: the hon. Member for Ashfield (Lee Anderson), who cannot be here this afternoon but who led an important Westminster Hall debate on this subject two years ago, and the hon. Member for Dartford (Jim Dickson), vice-chair of the APPG.

Sepsis strikes indiscriminately, ruthlessly and with terrifying speed, without regard for background, class or, indeed, political allegiance. It is vital that we all stand united in our determination to tackle this deadly condition. It is a challenge that completely transcends party politics.

On Sunday, communities across the world marked World Sepsis Day. The international theme for this year could not be more apt: “Invest in Sepsis—Save Lives.” The World Health Organisation recognises sepsis as one of the leading causes of death and disability globally, estimating that sepsis-related illnesses account for one in every five deaths worldwide. In the United Kingdom, NHS England has made it clear that sepsis claims more lives each year than lung cancer and represents the second biggest killer in our hospitals after cardiovascular disease.

Every single year, an estimated 245,000 people in the UK develop sepsis and, tragically, more than 48,000 lose their lives. That is a higher annual death toll than bowel, breast and prostate cancers combined. Behind every one of those figures is a family left grieving and asking the same agonising question: what if? What if the symptoms had been recognised an hour earlier? What if antibiotics had been administered sooner? What if someone had simply asked, “Could it be sepsis?”?

Madam Deputy Speaker, as you know, I do not approach this debate purely as a parliamentarian dispassionately analysing policy responses to one of the leading causes of avoidable death. I stand in this Chamber today because almost a decade ago, by the grace of God and the extraordinary skill and care of NHS staff, my life was saved.

In January 2017, I was a relatively fit and active 40-year-old Member of Parliament. I had developed what I assumed was merely a winter infection. Like many people would, I assumed that I could push through it, take some paracetamol and carry on working. I travelled out to Strasbourg to take part in the Parliamentary Assembly of the Council of Europe on the Sunday evening, but within days my condition collapsed. An ordinary throat infection triggered a catastrophic immune response. My body, in attempting to fight the infection, began attacking its own tissues and organs.

By Thursday, after seeing a French GP, I flew back to Britain. On Friday, I attended the official launch of the local enterprise zone that I had campaigned hard for in my constituency, but as soon as I arrived there I was so ill that I had to rest in the back room. On Saturday morning, I got out of bed, started putting my suit on over my pyjamas and told my wife Laura that I had to come down to Westminster to vote. Like many in politics, my behaviour can at times appear to some people to be a little idiosyncratic; fortunately, Laura realised that, even for a Member of Parliament, that was not entirely normal behaviour.

Laura rushed me to Russells Hall hospital in Dudley, where my blood pressure plummeted into septic shock and my organs began shutting down. My life was hanging by a thread. The medical team had to place me in a medically induced coma. Doctors told my family that my chances of pulling through were no better than one in 10.

For 11 days, I lay in intensive care on life support—or, as my family sometimes remind me, I slept through the difficult bits. When I did finally wake up, my muscles had wasted away—I could barely lift my arms, let alone stand or walk—but it could easily have been so much worse. What if Laura had left me to get some rest that Saturday morning while she took our daughter to her dance class? Above all, what if the nurse who examined me at the accident and emergency department had not had the insight to check whether the symptoms, which could easily have been mistaken for other illnesses such as flu or meningitis, might be sepsis? I owe a debt of gratitude to the doctors, intensive care nurses and other staff at Russells Hall hospital that I can never repay, but as long as I have the honour of serving in this House, I will use my voice to fight for sepsis patients and their families.

There is a common misconception that sepsis is primarily the result of hospital-acquired infection, but the evidence demonstrates the exact opposite. A major 2024 population study led by Professor van Staa, analysing linked primary care and hospital data in England, showed that the vast majority of sepsis cases are community acquired, developing in homes, workplaces and local communities long before a patient reaches an acute hospital bed. That research also uncovered deep health inequalities in sepsis risk.

The risk of developing sepsis is significantly heightened by socioeconomic deprivation, by frailty, by being housebound and by chronic conditions such as cancer, diabetes and learning disabilities. Exposure to antibiotics in the previous two months was also identified as a strong risk factor. While ethnicity was not an independent biological factor, black and Asian individuals suffer from a higher prevalence of predisposing conditions including diabetes, chronic liver disease and severe anaemia, which puts them at a greater risk, so tackling sepsis is not merely a technical, clinical issue but a fundamental challenge of health inequality and community prevention.

One of the most critical clinical lessons learned in recent years is the direct link between viral infections and sepsis. For decades, the public and the medical community viewed sepsis almost exclusively as a bacterial complication, but the covid-19 pandemic demonstrated that viral infections can trigger the exact same catastrophic septic response. The overwhelming cytokine storms, microvascular clotting and rapid progression to acute respiratory distress syndrome and multi-organ failure seen in covid intensive care units are classic manifestations of viral sepsis. It is thought by many experts in the field that the vast majority of covid deaths were a direct result of septic reactions.

Sepsis is not defined by the pathogen; it is defined by the body’s life-threatening immune reaction to any severe infection, whether bacterial, viral or fungal. That reality extends directly into long-term recovery: millions who had covid-19 are still living with long covid. Sepsis survivors have known that reality for generations under the name of post-sepsis syndrome. In my case, it is little more than some nerve damage and tiredness, even a decade later, but for many the symptoms are more severe. Up to 50% of sepsis survivors suffer prolonged physical, cognitive and psychological impairments from debilitating fatigue and cognitive brain fog to severe muscle weakness and post-traumatic stress disorder. The clinical insights gained from viral sepsis during the pandemic must now be used to build integrated recovery pathways for all sepsis survivors.

To curb preventable deaths, a health system must act decisively in several areas; in the interests of time, I will go through just four. First, the system must ensure consistent rapid recognition. Time is the single most decisive factor in sepsis survival. Clinical research shows that administering appropriate antibiotics within the first hour of a patient presenting to an emergency department with sepsis reduces the risk of death by a full one third compared with delayed treatment.

Secondly, the system must ensure that where sepsis is suspected, appropriate clinical escalation pathways are in place. Where sepsis is suspected, early warning systems such as the national early warning score 2, or NEWS2, have saved countless lives, and the ongoing roll-out of Martha’s rule across NHS trusts, which has already saved thousands of lives, is vital in ensuring that patients and loved ones can trigger an immediate independent critical review when they sense deterioration.

Thirdly, we must take advantage of innovation in rapid diagnostics. We know that administering broad-spectrum antibiotics within the golden hour that I spoke of massively increases survival rates, but clinicians often face the dilemma of judging whether that is compatible with responsible antimicrobial stewardship. Deploying rapid molecular diagnostics, bedside biomarker technologies and wearable continuous physiological monitors can remove that guesswork, and provide targeted care before septic shock takes hold and it can be too late.

Fourthly, although Britain has in many ways led the way in developing and enhancing sepsis care and treatment, we must be open to learning from established international models and practices. Sweden utilises standard sepsis alerts to prioritise patients at triage, and implements mandatory post-discharge telephone follow-ups. France, where I was when I was taken ill, has since introduced an integrated national sepsis plan spanning pre-hospital recognition, emergency pathways and structured rehabilitation to help patients return to employment. Australia established a national sepsis clinical care standard built around seven quality statements, ensuring end-to-end consistency from triage through to survivorship. The publication in July of the sepsis modern service framework by NHS England and the Department of Health and Social Care is an important step towards doing that and learning the lessons from around the world; I warmly welcome it. The framework is one of the first to be published under the 10-year health plan. Its headline goal,

“to reduce deaths, severe complications and long-term harm from sepsis…by at least 25% by 2035”

is a target that every member of this House can endorse.
LD
Vikki Slade
Mid Dorset and North Poole
The hon. Gentleman is making a really moving speech. Although one in 100 cases of sepsis in adults is linked to meningitis, it is one in 10 for children—with harrowing consequences. One of those children is Hamish, who was a classmate of my nephew Louis in Sussex. He had all four limbs amputated, and I pay tribute to his resilience in getting on with life and going to university. Because of the link between vaccines and the prevention of sepsis, will the hon. Member join me in calling for the menB vaccine to be repeated for teenagers next year and every year until all children are protected, so we can reduce the risk of sepsis in young people?
Mike Wood
The hon. Lady makes a really important point. We know how these conditions can come round in a cycle. In order to break that cycle, we will need multiple years of vaccination.

The modern service framework contains a number of vital commitments, but I particularly welcome: action 4 on improving the audit and feedback of sepsis-related clinical data across trusts; action 5 on updating training for NHS staff, social care workers and unpaid carers; action 9 on optimising care pathways and expanding access to rapid diagnostics and specialist advice; action 11 on standardising digital specifications for early warning systems such as NEWS2; and action 12 on reviewing and addressing capacity gaps in critical and enhanced care.

A strategy on paper will not be enough to save a deteriorating patient on a cold winter weekend in an overcrowded emergency department. In the other place, my noble friend and our former colleague Lord Mackinlay of Richborough, who has spoken with enormous courage about his own life-altering encounter with sepsis, has repeatedly tabled written questions seeking clarity on how this framework will be delivered. Regrettably, the answers provided by Ministers in the Lords to date have been rather generic and vague, and lacking in operational detail. We cannot accept boilerplate responses on a condition that kills 48,000 people each year, so I have two direct questions that I hope the Minister will answer in her response to today’s debate. First, what are the specific milestone-driven timelines for the delivery of each of the actions set out in the modern service framework, and when will trusts and integrated care boards be expected to have these standardised pathways fully operational? Secondly, can the Minister assure the House that the Department of Health and Social Care is prepared to commit the dedicated investment required to make this framework work?

When we call for investment, we must be clear that funding sepsis care is not an open-ended cost. It is one of the most cost-effective investments that the Department can make. Sepsis currently places an enormous financial burden on the national health service and the wider economy. Too often, cases of missed or delayed diagnosis and treatment result in weeks of high-cost intensive care unit admissions, in emergency readmissions due to incomplete recovery, in complex surgical interventions including amputations requiring lifelong prosthetic and social care support, or in the permanent loss of working-age adults from the workforce. Investing in rapid bedside diagnostics, digital early warning systems, specialist outreach teams and structured post-sepsis rehabilitation can dramatically reduce the lengths of stay in intensive care, lower readmission rates and keep people in work. Early intervention is not only clinically imperative; it is economically sound, and the theme “Invest in sepsis—save lives” is a call for smart preventive healthcare investment.
Lab
Dr Allison Gardner
Stoke-on-Trent South
Prevention is key, and an estimated 20% to 30% of sepsis cases are urosepsis. I have just learned today from my campaign with Good Housekeeping magazine of a gentleman who lost his wife due to urinary tract infection-related sepsis. Does the hon. Gentleman agree that if we are to really tackle sepsis, we also need to look at infection sources and get better diagnostics and treatment for those, particularly for ones such as UTIs, that are still not properly focused on?
Mike Wood
Absolutely. Of course, some infections are almost unavoidable, but where infections such as UTIs can clearly be reduced with the right care and precautions, we must do everything we can to reduce those risks.

Every Member in this Chamber has constituents whose lives have been permanently transformed by sepsis. Some Members have been directly impacted or have watched as close family and friends have encountered sepsis. We know the speed with which it strikes, but we also know that with early detection, immediate treatment and high quality critical care, thousands of lives can be saved. We have the clinical evidence and we have the modern service framework. What we now need is clear delivery timelines, rigorous parliamentary accountability and the necessary financial backing to make this ambition a reality. If the Minister can deliver this and provide the resources and tools that the NHS needs to implement it, the modern service framework truly can be a turning point in the fight against this silent killer and the battle to save thousands of lives.
Caroline Nokes
Madam Deputy Speaker
Before we move on, I want to pay tribute to the hon. Member for Kingswinford and South Staffordshire (Mike Wood) for his bravery in sharing his personal story and, of course, to the noble Lord Mackinlay in the other place, who has spoken on this subject so often and with such power.
Lab
Jim Dickson
Dartford
I am pleased to co-sponsor the debate alongside the hon. Members for Kingswinford and South Staffordshire (Mike Wood) and for Ashfield (Lee Anderson), both of whom are fellow officers of the all-party parliamentary group on sepsis. I pay tribute to the hon. Member for Kingswinford and South Staffordshire for that amazingly moving and revealing speech and for sharing his experience in a way that I hope all Members will take note of and that will make a difference to the way the Government take these issues forward. I am grateful to the Backbench Business Committee for granting time for this debate on Sepsis Awareness Month, with World Sepsis Day having taken place on Sunday.

I was pleased to welcome my constituent, John Snow, to Parliament last year and am extremely appreciative that he is with us today in the Gallery, alongside his wife Karen and his daughter Gracie. John developed sepsis in 2024. After first believing he was suffering with muscle pain, the situation rapidly deteriorated, resulting in hospital admission with heart attack-like symptoms and his lips turning blue. John and Karen were not aware at this point that John had many of the signs of sepsis. Within hours, his kidneys had shut down, needing dialysis, and his body went into septic shock with doctors putting him into an induced coma. It was unclear if John would survive, and the coma lasted for two weeks, during which time John was transferred from Darent Valley hospital in Dartford up to St Thomas’s just across the river from where we are now.

After a month, thankfully, John pulled through. But this good news was accompanied by the desperately difficult decision from his doctors that he needed to have a quadruple amputation. He has received amazing support from the Dartford community, which has rallied round to help fund support for his family. A special mention must go to the wonderful Dartford working men’s club, led by the amazing Nick Byram. The club not only held fundraisers for the family but has held sepsis awareness events to ensure that more people know the symptoms.

Notwithstanding this great community effort, there remains so much to do to improve post-infection support for people like John. I have been privileged to have kept in touch with John and Karen during John’s exceptionally brave recovery journey. When we met in July, he told me of the exceptionally long delay he was experiencing in receiving his new prosthetic hand. John was cast for the prosthetic at the end of last year, but due to issues relating to the move of his local prosthetic centre, it was not assembled, leaving him worried that his body may change and the prosthetic would not fit. The challenges that causes are compounded by the fact that he cannot have the casting for the second prosthetic hand until he has had the first one for a year—a timer that has not yet been able to start. John has also experienced delays and dysfunctions with his facial surgery, which he is currently undergoing with the support of surgeons and doctors.

John’s case illustrates how much we have to do to spread knowledge about sepsis and to improve care for those who have it. As others have done, I commend the campaigning work of Lord Mackinlay of Richborough, who has not only helped to raise awareness of sepsis in our health system, but has met John and provided encouragement to him in his recovery journey.
Vikki Slade
I too pay tribute to Lord Mackinlay because when Hamish’s story made the papers, he did not hesitate to visit Hamish, an 18-year-old, and help him through his recovery. When I first met Lord Mackinlay myself in Buckingham Palace when we had just been elected, I went to him and said, “What a hero. What an incredible man to do that every time a similar case happens.”
Jim Dickson
What the hon. Member and I have described is the mark of the man. Not only has he suffered that appalling setback in his life, come through it with huge brio and is an active Member of the other place, he has gone the extra mile to help others in the same predicament. I cannot thank him enough for the work he has done for those who have experienced sepsis and for my constituent John.

As Craig himself would say, sepsis remains something we do not know enough about, and what knowledge we have is not as widely known as it should be. I thought it would be helpful to remind all those present and anybody watching of the signs to look out for in adults, as set out by the UK Sepsis Trust: slurred speech or confusion; extreme shivering or muscle pain; passing no urine in a day; severe breathlessness; it feels like you are going to die; and skin mottled or discoloured. If you or another adult develops any of those signs, it is important to seek urgent medical attention.

John’s story highlights both the work we need to do to raise awareness of the early signs of sepsis and how we support those who have been diagnosed with it. There remains too little data on sepsis, with inconsistencies in the definitions used across the country. Office for National Statistics data indicates that sepsis was mentioned on the death certificate in 27,971 deaths in England in 2025, but that is almost certainly not the full story.
Dr Gardner
There is also the issue that the infection source is not recorded. Does my hon. Friend agree that we need to make significant improvements to this if we are to prevent sepsis? It is a slight repetition, but the lack of data collection worries me.
Jim Dickson
Absolutely. The data problems are much wider than simply understanding who has died with sepsis as a related cause and who has suffered sepsis at some point in the system. All the prevention and early diagnosis issues that my hon. Friend has highlighted go to the heart of the problems we have with data, and I hope the Minister will address that in her response.

I very much welcome the sepsis modern service framework, which was published last July and contains a much-needed plan to improve prevention, recognition, diagnosis, treatment and recovery for people affected by sepsis. It should mean that doctors are equipped to spot sepsis sooner and improve outcomes for patients like John and others who have been mentioned this evening. I hope the Minister will outline how the modern service framework will change the way the NHS supports John and others recovering from sepsis, so that the delays he has experienced in getting his prosthetics and the delays other people have experienced in the system become a thing of the past.
Lab
Ms Julie Minns
Carlisle
I am grateful for the opportunity to contribute to this very important debate during Sepsis Awareness Month; I pay tribute to the hon. Members for Kingswinford and South Staffordshire (Mike Wood) and for Ashfield (Lee Anderson) and my hon. Friend the Member for Dartford (Jim Dickson) for securing it.

The danger posed by sepsis cannot be overestimated. As we have heard, five people lose their lives to sepsis every single hour, and my mother was one of those it claimed last year. Deaths from sepsis rise sharply in the over-65s. Older people are more vulnerable to sepsis because ageing weakens the immune system, increases the likelihood of chronic illness and infection, and reduces the body’s ability to recover from severe infection, making sepsis more likely to become life-threatening.

I am acutely aware at my age that one of my significant organs is visually fading and failing, and that is my skin. The serious point is that, as our skin fails, the increased risk of cuts, tears and the formation of ulcers becomes ever more prevalent, all bringing with them the attendant risk of infection. That, sadly, was the case for my mother. That sepsis is the second biggest killer after cardiovascular disease is evidence of why awareness is so important. The earlier sepsis is recognised and appropriate help sought, the better the chance of preventing a devastating outcome.

I want to use this debate to share the experience of one of my Carlisle constituents, Kelly Pattison. Kelly developed biliary sepsis in December last year. She describes how she did not know she had it until she woke up on a ward, having spent three days in intensive care. Kelly’s story is an important reminder of just how unpredictable and unexpected sepsis can be. What she particularly wanted me to emphasise today is that there is no one single experience of sepsis; it can affect people in very different ways, and the seriousness of what is happening may not always be immediately obvious.
Lab
Sureena Brackenridge
Wolverhampton North East
There is really good practice across other countries, including Australia, which has a national sepsis standard, standardised clinical pathways and a public awareness campaign, similar to ours, which is aligned with the simple question: “Could it be sepsis?” Work that has reduced sepsis mortality has been happening around the globe, so does my hon. Friend agree that it is worth looking beyond our borders?
Ms Minns
My hon. Friend raises an important point, and I agree that the more best practice available elsewhere that we can bring to our country, the better.

Awareness cannot stop at the point of diagnosis. Surviving sepsis can be a major event in someone’s life, and the effects can continue well beyond the immediate illness. Patients and their families may need information, support and help as they recover. That is why I welcome the Government’s sepsis modern service framework. It represents an important step forward in how we approach this condition, setting out a long-term plan to improve sepsis care across prevention, recognition, diagnosis, treatment and recovery, with the ambition of reducing deaths, life-threatening complications and the long-term effects of sepsis by at least 25% by 2035. That ambition is significant. The success of the framework will be measured in earlier recognition, prompt treatment and ongoing support for survivors who need it.

The framework’s focus on better data, research and innovation is particularly welcome. Improving how we identify sepsis, developing faster and more accurate diagnosis and learning from patients’ experiences can all help clinicians to intervene earlier and improve outcomes. I hope that through the sepsis modern service framework we can ensure that when people do seek help, they are heard, sepsis is recognised as early as possible, and they receive the care and support that they need.
Caroline Nokes
Madam Deputy Speaker
That brings us to the Front-Bench contributions. I call the Liberal Democrat spokesperson.
LD
Dr Danny Chambers
Winchester
I pay tribute to the hon. Member for Kingswinford and South Staffordshire (Mike Wood) for so vividly highlighting his personal experience of sepsis. He gave a very emotional speech and it is good to see him in the Chamber looking so healthy.

Around one in five deaths worldwide are associated with sepsis—that is 11 million deaths a year. I recently met Ron Daniels, founder and chief medical officer of the UK Sepsis Trust, to discuss the new sepsis modern service framework. I very much welcome its ambition to reduce deaths, life-threatening complications and the long-term impact of sepsis by at least 25% over the next decade, but if we are serious about achieving that, we need to get much better at detecting infection early.

Sepsis is the body’s extreme response to infection, whether viral, bacterial or fungal. It can cause organ failure, permanent disability and death. Crucially, patients can deteriorate incredibly quickly. There is no single diagnostic test for sepsis; its symptoms overlap with many other conditions and clinicians are often having to make decisions with incomplete information. That is why rapid diagnostic tests are so important. I recently held a meeting at Winchester hospital for local GPs, the local authority, laboratories and manufacturers of various rapid diagnostic tests to look at the barriers to implementing rapid diagnostic tests, and at how people can have them in the community for earlier diagnosis and the prevention of hospital admissions.

Better diagnostics mean earlier treatment. They mean being able to use the right antibiotic for the right infection; they mean preventing patients deteriorating into sepsis; and they mean using fewer unnecessary antibiotics, which ultimately can result in antimicrobial resistance developing and is another huge growing public health concern.

Prevention matters too. We must reverse the falling vaccination rates that we have seen in recent years to prevent infections occurring in the first place, as well as ensuring that hospitals have the facilities to isolate and care properly for infectious patients. Crucially, it also means tackling corridor care and long waits in A&E, because when somebody is deteriorating in those conditions, every hour matters, as we know. In the case of corridor care and long waits, that means that diagnosis and treatment is more likely to be delayed.

I wish to talk specifically about one group of patients—cancer patients. We rightly focus on treating the cancer itself, but infection, often sepsis, is the second-biggest cause of death for people with cancer. That may seem surprising, but cancer can cause a reduction in people’s immunity. Chemotherapy and various treatments cause people to become immunocompromised, weakening their immune system and making them more prone to getting infections. That also means repeat infections, which means that they are more likely to have repeat uses of antibiotics and to have antibiotic-resistant infections.

The consequences of infection for people with cancer can be even more serious. That is why I find one omission from the Government’s national cancer plan quite striking. It is an 86-page strategy setting out how we are going to transform cancer care by 2035, yet infection is mentioned only once, and that is just in the foreword. That is not a minor oversight; it is a glaring omission that risks undermining the entire cancer strategy. We would never produce a cancer strategy that treated radiotherapy, chemotherapy or surgery as peripheral to cancer care, so we need to ensure that we are treating infection, which is the second-biggest killer of cancer patients, as integral to cancer care. Infection prevention, rapid diagnostics, antimicrobial stewardship and surveillance need to be absolutely central to cancer care, not an afterthought. If we fail to address infection properly, we are setting the entire new cancer strategy up to fail.

Sepsis contributes to tens of thousands of deaths in the UK each year, as well as leaving many survivors with life-changing physical and psychological consequences. I have one specific request of the Government. Will the Minister commit to updating the national cancer strategy to incorporate infection control, sepsis and rapid diagnostic tests as being absolutely integral to cancer management? We welcome the new sepsis modern service framework; we just need to deliver it.
Caroline Nokes
Madam Deputy Speaker
I call the shadow Minister.
Con
Dr Caroline Johnson
Sleaford and North Hykeham
I start by declaring my interest as an NHS consultant paediatrician, a member of the Royal College of Paediatrics and Child Health, a member of the British Medical Association and a mother of three children.

I congratulate my hon. Friend the Member for Kingswinford and South Staffordshire (Mike Wood) on securing this debate, alongside the hon. Members for Dartford (Jim Dickson) and for Ashfield (Lee Anderson). In particular, I thank my hon. Friend for his speech, which was hugely moving. I cannot believe that it has been such a long time since his illness happened, but it is great to see him looking so well today. I express my condolences to the hon. Member for Carlisle (Ms Minns) and thank her for the brave speech that she gave.

I remember sitting in this Chamber a little over two years ago—I am sure you were there too, Madam Deputy Speaker—when the then Member for South Thanet, now Lord Mackinlay, received a rare standing ovation from the House and from the Gallery as he returned to Parliament following his remarkable recovery from sepsis. His journey has been incredible, and his story has brought renewed attention to a disease that kills nearly 50,000 people every year. For context, that is around the same number of people who die from bowel, breast and prostate cancer combined. However, with attention to prevention, early identification of infection, early diagnosis, better treatments and the avoidance of antimicrobial resistance, we can reduce that number and save people’s lives.

As I said, raising awareness of sepsis and how suddenly it can change someone’s condition is vital, and the previous Conservative Government got the ball rolling in that regard. My right hon. Friend the Member for Godalming and Ash (Sir Jeremy Hunt) adopted the UK Sepsis Trust’s “Just ask ‘Could it be sepsis?’” campaign in 2016 when he was Health Secretary. The Conservatives also backed sepsis research with more than £1 billion through the National Institute for Health and Care Research. Research is important, because it will help us to improve diagnosis and treatment and to better understand why some people get an infection and it makes them a little bit ill, but some people get an infection and it turns into sepsis.

That was a good start, but of course, as always with medicine, there is more to do, and it was pleasing to see the previous Starmer Government build on this work by introducing the modern service framework for sepsis. We have modern service frameworks for other diseases, and it seems good to have one for sepsis specifically. The guiding light of this framework is the Government’s ambition to reduce sepsis deaths by 25% by 2035, with which I think we could all agree. But simply saying it will not deliver it; it has to have a plan, and the plan has to be deliverable and funded. What funding have the Government committed to implement that framework?

As we know, early diagnosis is paramount, but sepsis is notoriously difficult to diagnose and very rapid. I remember seeing a patient whose mum had got up in the middle of the night to use the bathroom—not something she did normally, and she was not quite sure why she had on that particular night—and when she was walking back along the landing, she thought, “It’s a bit cold—I’ll just check.” She checked her son had his blankets on and was warm, but as she did so, just in the light from the landing she spotted a little mark on the little boy’s leg. She turned the light on, and saw that he was developing the rash, which does not blanch, that goes with meningococcal sepsis. She brought him in, and he survived and he went home well, but I shudder to think what would have happened if she had waited till she woke up routinely at 7 o’clock in the morning. So someone was watching to make sure he was safe, and I am so glad that was the case, but it is so very rapid, as others hon. Members have testified.

There is no single test. There is no single thing we can monitor or measure that helps. Flu-like symptoms mimic many other common illnesses, and on top of that, as we have heard, diagnosis and treatment are absolutely time-critical. The UK Sepsis Trust has developed the sepsis six—oxygen, cultures, antibiotics, fluids, lactate management and urinary output monitoring—and all these should be carried out within the first hour. The Government’s MSF commits to rapid diagnostic tools and more advanced genomic sequencing. What infrastructure and workforce investment is required by the Government to set this up, and over what timeframe do they envisage that it will be achieved?

Talking about the workforce, the Government decided to ditch the previous Government’s NHS workforce plan to create their own, which is of course their right. However, their replacement was originally due to be published in early 2025 and was most recently promised as “imminent” just before the summer recess, but we are now well into September 2026 and there is still no plan. The Minister in the other place was asked for more details about the workforce plan, but her written answer simply stated that the Government

“will provide an update on the 10 Year Workforce Plan in due course.”

Could the Minister please update us on when this plan is going to be published, preferably with a date rather than an expression of “soon” or “imminent”?

I want to mention group B streptococcal infection, which I have seen in paediatric practice, particularly in babies. It is a common bacteria that lives harmlessly in the gut or lower reproductive tract, but there is a risk that it can enter the bloodstream, causing neonatal sepsis when passed to newborns. The GBS3 trial is looking to prevent and reduce the impact of group B strep, and the Government’s framework commits to supporting that. Could the Minister tell us more about how the Government plan to do that?

I also want to talk about prevention, which the Government have said is one of their big shifts in medicine. Some sepsis can be prevented or reduced, and research has shown that, for example, if ibuprofen is given to children with chickenpox, it increases the likelihood of their developing sepsis. We know that completing the antibiotic course is important. We also know that handwashing technique is important, and that keeping things clean is important, particularly in preventing the sepsis that is acquired in hospitals. Management of chronic disease reduces the risk, too, and then there is vaccination.

Meningitis B is possibly one of the most scary infections and conditions that one sees as a doctor, because it progresses so quickly—and it can cause brain damage, amputations and death—but there is a highly effective vaccine, which was introduced for infants born from the middle of 2015 onwards. However, as the outbreak in Kent, Dorset and Berkshire showed last year, when three young people died, it can still come back in older children.

The Joint Committee on Vaccination and Immunisation met in July 2026 and suggested an increase in the vaccination schedule for those young people. It recommended that young children who had had one dose of vaccine should have another at age 15; that those who had not had the vaccine should have two doses; and that older people starting university should have a catch-up.

Very shortly, it will be freshers week, and around 580,000 young people will head off to university for the first time with great excitement. University students are seven times more likely to get invasive meningococcal sepsis than people who do not go to university, and the Government have only managed to vaccinate 246,000 of those young people—something that the UK Health Security Agency issued a document about last week. It said that last year, 97% of invasive meningococcal disease in 15 to 24-year-olds was caused by meningitis B, so I will ask the Minister some questions that I asked her during last week’s vaccine debate and have not yet received an answer to. When is she going to review and respond to the requests for vaccines for younger children who have not had them yet—the doses at 15 and the two doses for those who have not had a dose yet? What is she doing to increase awareness among people starting university in the next week or so?
Vikki Slade
I am really grateful to the shadow Minister for raising this issue, which I also raised earlier in the debate. My son George and his girlfriend Maisie both had their two doses in the past few weeks as they turned 18, but my constituent Victoria asked me to write to the Minister a few months ago about education and awareness. I was really disappointed that the Department for Education did not think it was necessary to add meningitis awareness into the personal, social, health and economic education programme in secondary school. Will the shadow Minister support me in advocating for that?
Dr Johnson
It is clearly important that young people are aware of the signs of infection, particularly such a serious infection, so I agree with the hon. Member about that.

I am interested in what the Minister is doing to try to prevent these infections by ensuring that the right people have the right vaccines. The Government are changing the way in which vaccines are being commissioned from NHS England, which they are abolishing. [Interruption.] Madam Deputy Speaker seems to have a cough, so I will finish my speech. The integrated care boards are going to be responsible for vaccinations. How is that change going to impact vaccines, particularly for students who live in one place and go to university in another?

To sum up, the Government’s ambition to reduce sepsis and sepsis deaths should be welcomed, and it is good to have the modern service framework in place. However, I am sure that charities such as the UK Sepsis Trust and families affected by sepsis would be most grateful if the Minister could provide further clarity on the Government’s road map and the funding required to reach this important destination.
Dame Diana Johnson
The Minister for Public Health and Patient Safety
I start by congratulating the hon. Member for Kingswinford and South Staffordshire (Mike Wood) on securing this important debate on the Floor of the House of Commons from the Backbench Business Committee during Sepsis Awareness Month. I also thank him for his tireless advocacy on sepsis as the co-chair of the APPG. In his excellent opening speech, he spoke very movingly about his own experience. He said that consultants gave him a 10% chance of survival when he was ill with sepsis, so the odds were that he would not be with us today, but I am very grateful that he is and that he is looking so well, and that he can be such a strong voice in this place on sepsis.

I also compliment Lord Mackinlay on the work that he carries on in the other place. Like the shadow Minister, I remember the standing ovation he received when he returned to the House of Commons after battling life-threatening sepsis in 2023, resulting in four limb amputations—what a brave and decent man! Many tributes have been paid to him across the Chamber this afternoon.

I will refer to some of the contributions that have been made. My hon. Friend the Member for Dartford (Jim Dickson) spoke powerfully on behalf of his constituent John, who fought sepsis and is a quadruple amputee. He talked very movingly about how the community had rallied around the family to provide support, but also spoke about how we need to do much more to support people like John in the post-recovery period.

My hon. Friend the Member for Carlisle (Ms Minns) spoke eloquently about her mum, who she lost to sepsis last year—I hope she will accept my condolences—and also her constituent, Kelly Pattison. She reminded us that sepsis affects people in different ways and how important it is to remember that. The hon. Member for Winchester (Dr Chambers), who speaks on behalf of the Liberal Democrats, highlighted the particular risks that people with cancer face from sepsis. I will certainly take back to the Department the concerns that he has raised today.

Sepsis is a devastating condition. It also costs the NHS significant sums of money—more than £1 billion between 2024 and 2025. During Sepsis Awareness Month, I pay tribute to the charities, such as the UK Sepsis Trust and Sepsis Research FEAT, that do so much to support families, raise awareness and fund research. Their contribution to the new sepsis modern service framework was invaluable, and they acted as a megaphone for so many people whose lives have been devastated by sepsis. My deepest condolences go out to everyone who has been affected, not least Merope Mills and other campaigners, but I know that people are not seeking my sympathy today; they want the Government to support the case they are making.

Turning to the sepsis modern service framework, we worked hand in hand with patient representatives, clinical experts, professional bodies, NHS organisations and charities to build the framework. It has entered the history books as the first-ever large-scale engagement process for improving sepsis care. The framework spells out this Government’s commitment to transform sepsis care by 2035. It sets out priority actions to improve prevention, recognition, treatment and recovery while accelerating innovation.

I completely understand that people will say, “Okay, you have now got the framework. What happens next?” We are going to make real progress, and by doing that, we are going to raise our game in a number of areas, including science, technology and data. The National Institute for Health and Care Research, working with academia, industry and other partners, will develop a national research and innovation action plan for sepsis by March next year. That will include research calls that cover sepsis improvement priorities, whether it is vaccination and screening, faster and more accurate diagnosis or innovative treatments.

It is true that the most recent data from the Office for National Statistics suggests that sepsis deaths went down in 2024. However, the data is incomplete and inconsistent. That is due to changes in awareness, diagnosis and recording, making it harder to understand variation and improve care. Without that data, we do not have a full picture, and that is why the framework commits to collecting better sepsis data and why NHS England is commissioning a national infection and sepsis audit. That should give us a clearer picture of mortality, underlying causes and which groups are most affected.

Turning to understanding, it is right to say that Members have highlighted that sepsis is a complex condition that is difficult to recognise because of the variation in symptoms. Many people are unaware that sepsis can develop from common infections, such as urinary tract infections, and few can recognise the full range of symptoms. That is precisely why raising awareness is so important. As we have heard from Members across the House today, the work of campaigners has had a huge impact across the NHS and wider society. The NHS now has a planned, targeted public communications campaign to improve awareness of sepsis symptoms and the actions to take.
Con
Greg Smith
Mid Buckinghamshire
As was mentioned earlier, the UK Sepsis Trust had a big bang in 2016 with the famous orange and red posters saying, “Just ask ‘Could it be sepsis?’”, which can be seen in many GP surgeries, hospital waiting rooms and so forth. However, those information campaigns dwindle; they become samey, and people get used to seeing them and then not thinking about them. How can the Government organise an almost permanent campaign that refreshes awareness of such a huge killer in our country in the minds of the clinicians and doctors who do such wonderful work, but are under such incredible pressure that they need a constant reminder of conditions such as sepsis?
Dame Diana Johnson
I entirely take the hon. Gentleman’s point. We are working all the time on maintaining good public campaigns on issues such as this, and we are reviewing what works and the best methods to use. A campaign of this kind should not be limited to one point in time; it must be ongoing.

The NHS has got better at recognising and responding to all causes of deterioration, including sepsis, since the introduction of the national early warning score. This system helps to identify patients who are seriously ill through clear, scored measurements that are routinely recorded by their bedsides. It is used by every ambulance trust and 99% of acute trusts in England, and the sepsis modern service framework will improve the consistency of its use. To further support the way in which we identify sepsis, the framework prioritises advances in faster, more accurate diagnosis to improve outcomes and the correct use of antibiotics. It will support better access to rapid tests in urgent and emergency care to tackle the problems that occur with the services that are often under the most pressure, where sepsis can slip through the cracks. In the longer term, the Government are promoting wearable health technologies as part of our 10-year plan. The framework will also explore new point of care tests that can determine exactly what kind of infection someone may have, alongside the use of those wearable technologies to support the monitoring of high-risk groups.

No one knows a child better than his or her parents or carers, which is why listening to patients, carers and families is vital to supporting sepsis recognition and escalation. Too many cases have shown the devastating consequences when deterioration concerns are not heard. The death of Martha Mills was an avoidable tragedy, but I hope that her parents take some consolation from knowing that Martha’s rule is saving lives and helping thousands of patients to benefit from changes in their care. I thank them for their tireless campaigning in Martha’ memory, and the real change that it has brought.

Let me remind the House that Martha’s rule means that patients, their families and staff can request a rapid review from a different team if deterioration concerns are not being recognised. Between September 2024 and June this year, nearly 17,500 Martha’s rule calls were made, 5,000 of which were made when a family feared that their loved one’s condition was deteriorating rapidly. Of those, 60% required changes in treatment, with 13% leading to transfers to intensive care and 47% leading to other care changes, including investigations and procedural interventions. Today, Martha’s rule is being rolled out in all acute hospitals in England.

As Members have pointed out this afternoon, it is important to note what happens to people who survive sepsis. They may experience a range of long-term physical, psychological and cognitive health consequences. As the Secretary of State has said, the NHS is cradle to grave, and that means everything in between. It is not acceptable that when someone has been through the worst experience of their life, they are just left to get on with it. That is why we are committed to improving access to post-discharge support and rehabilitation, with priority actions set out in the framework.

Of course, the best way in which to stop sepsis is to prevent infection. Vaccination and infection prevention and control are fundamental. As was mentioned earlier, the outbreaks of meningitis B in England this year demonstrated how quickly infection can lead to sepsis and death. Those outbreaks highlighted the importance of prompt treatment and the benefits of vaccination. The one-off NHS menB vaccination programme has successfully delivered nearly 250,000 first doses to eligible young people across England since its launch on 20 July 2026. I encourage everyone who has not yet come forward to do so, and to ensure that they obtain both doses of the vaccine for proper protection.

The framework commits to improving vaccine access. The shadow Minister put a number of questions to me. I will respond in writing, as I am conscious of the time. The framework also recognises the tension between prompt antimicrobial treatment for sepsis and the risks of unnecessary antibiotic use, and it complements initiatives within the antimicrobial resistance national action plan.

The hon. Member for Kingswinford and South Staffordshire raised a specific question about funding. I want to make it clear that the immediate and short-term actions will be delivered within existing funding under the current departmental allocation, following the 2025 spending review. Longer-term funding is subject to future spending reviews. The Department and NHS England are committed to prioritising funding for sepsis in future spending bids. The framework is a 10-year plan. I do not pretend that we will deliver everything overnight, but it sets clear targets to reduce deaths by a quarter over the next 10 years. That is a clear metric by which to judge our success and to hold Ministers to account. Implementation will be overseen by the National Quality Board.

In conclusion, it has become a bit of a cliché to say things like, “World Sepsis Day is marked once a year, but our work continues all year round.” However, I can assure hon. Members that the sepsis modern service framework is doing just that. For every single day over the next 10 years, the framework will keep pushing us to do better. Let me end by again thanking the hon. Member for Kingswinford and South Staffordshire for securing the debate and for his leadership of the APPG. I look forward to working with him constructively going forward.
Mike Wood
I thank all hon. Members who contributed to the debate.

The hon. Member for Dartford (Jim Dickson) spoke movingly about his constituent John. I was particularly pleased to hear how well he is now doing since recovering and about the support his family received from the community—in particular the work that Dartford working men’s club is doing in the community. If we are to really increase awareness so that people understand both the science and the risks of sepsis, it cannot be left to the NHS alone. It really does need to be a full community effort, so it is great to hear that the working men’s club is taking a lead. He also, rightly, spoke about the importance of data. Part of the problem is inconsistency in reporting sepsis cases. That makes it so difficult to have a meaningful figure for the number of cases, deaths and serious disabilities as a result of sepsis. We really need more consistency in the way that is coded, as well as a guide to best practice.

I join the Minister in offering my condolences to the hon. Member for Carlisle (Ms Minns) on the sad loss of her mother; it must have been an unbearably difficult time. She also spoke about her constituent Kelly, and gave us the very important message that different people experience sepsis very differently, both in terms of outcomes and the lasting impact, as well as the nature of their sepsis.

We heard important interventions from the hon. Members for Mid Dorset and North Poole (Vikki Slade), for Stoke-on-Trent South (Dr Gardner) and for Wolverhampton North East (Sureena Brackenridge). The Liberal Democrat spokesperson, the hon. Member for Winchester (Dr Chambers), referred to the force of nature that is Ron Daniels, who has done so much to push sepsis up the public agenda, and to change the way that the NHS understands and responds to sepsis. We all owe him a huge debt.

The shadow Minister, my hon. Friend the Member for Sleaford and North Hykeham (Dr Johnson), spoke about how notoriously difficult sepsis is to diagnose, and about the issues around prenatal strep and the additional work that needs to be done in both understanding and responding to the sepsis that arises. I thank the Minister for the kind words she offered to me, and for the spirit of her response, particularly around the implementation plan and funding. She rightly referred to Martha’s rule, and the importance of ensuring that families, who know their children better than anyone else, are allowed to insist on an independent second opinion if they feel that there has been a deterioration in condition.

I will briefly thank the many campaigners who have worked so hard on this issue—often because, sadly, they or a member of their family has been affected. They are too numerous to name, but I will mention the incredible work done by Harry Redknapp, who works tirelessly, and often without an awful lot of publicity and credit, to raise awareness of sepsis following his wife Sandra’s illness—I think he was in the jungle on “I’m a Celebrity...Get Me Out of Here!” when she was taken ill. Harry does so much incredible work voluntarily. Researchers and charities do incredible work, including Sepsis Research, and particularly the UK Sepsis Trust—both Ron Daniels and Sarah Hamilton-Fairley have helped to keep the issue rising to the level of importance it deserves.

I thank all Members for the valuable contributions they have made today, and I look forward to holding the Minister to account as she delivers on the modern service framework.

Question put and agreed to.

Resolved,

That this House has considered World Sepsis Awareness Month.

Contains Parliamentary information licensed under the Open Parliament Licence v3.0.